Plasma - based disinfectant capable of restricting spread of infectious diseases like COVID 19

New Delhi, Apr 19: Researchers have developed a plasma-based disinfectant generated with the help of cold atmospheric pressure plasma (CAP) which could act as a green decontaminant for COVID 19. A team of scientists Dr. Kamatchi Sankaranarayanan, Dr. Mojibur R. Khan, and Dr. H. Bailung is involved in the research.

 

 

 

The COVID 19 pandemic had brought forth the urgent need for decontaminants that can limit the spread of infectious diseases through contact. However, most decontaminants consisted of chemicals which are hazardous for the environment. This encouraged researchers to work towards greener alternatives.

 

 

A team of scientists Dr. Kamatchi Sankaranarayanan, Dr. Mojibur R. Khan, and Dr. H. Bailung from the Life Sciences and Physical Sciences divisions from the Institute of the Advanced Study in Science and Technology (IASST) has demonstrated that the plasma generated by cold atmospheric pressure (CAP) has the potential to deactivate SARS-CoV-2 spike protein, which binds to human ACE2 receptor for inducing viral infection and subsequent COVID 19.

 

 

 

 

 

Plasma, the fourth state of matter which makes up most of the universe when produced in controlled conditions in the lab and are termed as Cold Atmospheric Pressure Plasma (CAP). The scientists passed plasma forming gases such as Helium, Argon, and Air through a high voltage electric field which led to the formation of a stable plasma with a mixture of ions, and electrons emitting a pink glow of CAP inside the reaction chamber.

 

The research was recently published in the international journal of the RSC (Royal Society of Chemistry) Advances shows that short-lived highly reactive oxygen and nitrogen species (ROS/RNS) generated in the plasma led to complete deactivation of the SARS-CoV-2 Spike protein occurs within 2 min of CAP treatment. The RT-PCR analysis has also established that CAP can deactivate the RNA of the SARS-CoV-2 virus.